BDBM50311674 (4bR,10bS,12aS)-9-chloro-8-hydroxy-12a-methyl-2,3,4,4a,5,6,10b,11,12,12a-decahydrochrysen-1(4bH)-one::CHEMBL1081361

SMILES C[C@]12CC[C@H]3[C@@H](CCc4cc(O)c(Cl)cc34)[C@@H]1CCCC2=O

InChI Key InChIKey=JPMPZOSFYWJSOX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311674   

Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311674((4bR,10bS,12aS)-9-chloro-8-hydroxy-12a-methyl-2,3,...)
Affinity DataIC50: 77nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311674((4bR,10bS,12aS)-9-chloro-8-hydroxy-12a-methyl-2,3,...)
Affinity DataIC50: 770nMAssay Description:Displacement of [3H]17beta-estradiol from human ERalpha expressed in SF9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed