BDBM50311547 5-fluoro-2-(1-(6-(3-methoxyphenoxy)pyrimidin-4-yl)piperidin-4-yloxy)pyrimidin-4-amine::CHEMBL1076272

SMILES COc1cccc(Oc2cc(ncn2)N2CCC(CC2)Oc2ncc(F)c(N)n2)c1

InChI Key InChIKey=DEKRTLNHJYBYMD-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311547   

TargetDeoxycytidine kinase(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311547(5-fluoro-2-(1-(6-(3-methoxyphenoxy)pyrimidin-4-yl)...)
Affinity DataEC50:  36nMAssay Description:Inhibition of dCK in human CCRF-CEM assessed as inhibition of Ara-C phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetDeoxycytidine kinase(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311547(5-fluoro-2-(1-(6-(3-methoxyphenoxy)pyrimidin-4-yl)...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human dCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed