BDBM50311542 2-(1-(6-(benzo[b]thiophen-2-yl)pyrimidin-4-yl)piperidin-4-yloxy)-5-fluoropyrimidin-4-amine::CHEMBL1081561

SMILES Nc1nc(OC2CCN(CC2)c2cc(ncn2)-c2cc3ccccc3s2)ncc1F

InChI Key InChIKey=GYKYTDOMNQHWOH-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311542   

TargetDeoxycytidine kinase(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311542(2-(1-(6-(benzo[b]thiophen-2-yl)pyrimidin-4-yl)pipe...)
Affinity DataEC50:  700nMAssay Description:Inhibition of dCK in human CCRF-CEM assessed as inhibition of Ara-C phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetDeoxycytidine kinase(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311542(2-(1-(6-(benzo[b]thiophen-2-yl)pyrimidin-4-yl)pipe...)
Affinity DataIC50: 38nMAssay Description:Inhibition of human dCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed