BDBM50311489 2-{3-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2,2-dioxo-2,3-dihydro-2lambda*6*-benzo[1,2,5]thiadiazol-1-yl}-N-methyl-acetamide::CHEMBL1076242

SMILES CNC(=O)CN1c2ccccc2N(C2CCN(CC2)C2CCC(CC2)C(C)C)S1(=O)=O

InChI Key InChIKey=DJCHJXJTDJZMOI-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50311489   

TargetNociceptin receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50311489(2-{3-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2...)
Affinity DataKi:  6.40nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50311489(2-{3-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2...)
Affinity DataIC50: 21nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50311489(2-{3-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2...)
Affinity DataKi:  346nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed