BDBM50311476 2-(3-(1-((1r,4r)-4-isopropylcyclohexyl)piperidin-4-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-methylacetamide::CHEMBL1080484

SMILES CNC(=O)Cn1c2ccccc2n(C2CCN(CC2)[C@H]2CC[C@@H](CC2)C(C)C)c1=O

InChI Key InChIKey=LRZFEWAQPXYWOH-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50311476   

TargetMu-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50311476(2-(3-(1-((1r,4r)-4-isopropylcyclohexyl)piperidin-4...)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50311476(2-(3-(1-((1r,4r)-4-isopropylcyclohexyl)piperidin-4...)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50311476(2-(3-(1-((1r,4r)-4-isopropylcyclohexyl)piperidin-4...)
Affinity DataIC50: 59nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed