BDBM50311250 (S)-N-(5-phenyl-1-(phenylsulfonyl)pent-1-en-3-yl)-3-(pyridin-3-yl)isoxazole-5-carboxamide::CHEMBL1079067

SMILES O=C(N[C@@H](CCc1ccccc1)\C=C\S(=O)(=O)c1ccccc1)c1cc(no1)-c1cccnc1

InChI Key InChIKey=OGMBKJCSYTUQFC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50311250   

TargetCruzipain(Trypanosoma cruzi)
University of California

Curated by ChEMBL
LigandPNGBDBM50311250((S)-N-(5-phenyl-1-(phenylsulfonyl)pent-1-en-3-yl)-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi cruzain after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University of California

Curated by ChEMBL
LigandPNGBDBM50311250((S)-N-(5-phenyl-1-(phenylsulfonyl)pent-1-en-3-yl)-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain preincubated after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCathepsin B-like cysteine protease(Trypanosoma brucei)
University of California

Curated by ChEMBL
LigandPNGBDBM50311250((S)-N-(5-phenyl-1-(phenylsulfonyl)pent-1-en-3-yl)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Trypanosoma brucei Cathepsin B-like protease after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed