BDBM50311247 (S)-4-methyl-N-(5-phenyl-1-(phenylsulfonyl)pent-1-en-3-yl)-2-(pyrazin-2-yl)thiazole-5-carboxamide::CHEMBL1078779

SMILES Cc1nc(sc1C(=O)N[C@@H](CCc1ccccc1)\C=C\S(=O)(=O)c1ccccc1)-c1cnccn1

InChI Key InChIKey=ZJQRCBHYKYNYON-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50311247   

TargetCruzipain(Trypanosoma cruzi)
University of California

Curated by ChEMBL
LigandPNGBDBM50311247((S)-4-methyl-N-(5-phenyl-1-(phenylsulfonyl)pent-1-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi cruzain after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University of California

Curated by ChEMBL
LigandPNGBDBM50311247((S)-4-methyl-N-(5-phenyl-1-(phenylsulfonyl)pent-1-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain preincubated after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCathepsin B-like cysteine protease(Trypanosoma brucei)
University of California

Curated by ChEMBL
LigandPNGBDBM50311247((S)-4-methyl-N-(5-phenyl-1-(phenylsulfonyl)pent-1-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Trypanosoma brucei Cathepsin B-like protease after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed