BDBM50311076 CHEMBL1079079::[125I]1-(2-iodophenyl)-4-cyano-5-(4-methoxyphenyl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxylate

SMILES COc1ccc(cc1)-c1c(C#N)c(nn1-c1ccccc1I)C(=O)NN1CCCCC1

InChI Key InChIKey=WGIPGQAPFNVWIX-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50311076   

TargetCannabinoid receptor 1(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50311076([125I]1-(2-iodophenyl)-4-cyano-5-(4-methoxyphenyl)...)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50311076([125I]1-(2-iodophenyl)-4-cyano-5-(4-methoxyphenyl)...)
Affinity DataKi:  94nMAssay Description:Displacement of [3H]8OH-DPAT from 5HT1A receptor at 10 uM by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50311076([125I]1-(2-iodophenyl)-4-cyano-5-(4-methoxyphenyl)...)
Affinity DataKi:  548nMAssay Description:Displacement of [3H]CP-55940 from CB2 receptor by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50311076([125I]1-(2-iodophenyl)-4-cyano-5-(4-methoxyphenyl)...)
Affinity DataKi:  1.48E+3nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor at 10 uM by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50311076([125I]1-(2-iodophenyl)-4-cyano-5-(4-methoxyphenyl)...)
Affinity DataKi:  1.50E+3nMAssay Description:Displacement of [3H]DAMGO from mu opioid at 10 uM by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTranslocator protein(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50311076([125I]1-(2-iodophenyl)-4-cyano-5-(4-methoxyphenyl)...)
Affinity DataKi:  3.17E+3nMAssay Description:Displacement of [3H]PK11195 from TSPO at 10 uM by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50311076([125I]1-(2-iodophenyl)-4-cyano-5-(4-methoxyphenyl)...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]Iodoclonidine from alpha-2C adrenergic receptor at 10 uM by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed