BDBM50311031 CHEMBL1078933::N-(cyanomethyl)-4-(2-(4-((4-ethylpiperazin-1-yl)methyl)phenylamino)pyrimidin-4-yl)benzamide

SMILES CCN1CCN(Cc2ccc(Nc3nccc(n3)-c3ccc(cc3)C(=O)NCC#N)cc2)CC1

InChI Key InChIKey=HBTCPVXXBIMFAT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311031   

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311031(N-(cyanomethyl)-4-(2-(4-((4-ethylpiperazin-1-yl)me...)
Affinity DataIC50: 47nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311031(N-(cyanomethyl)-4-(2-(4-((4-ethylpiperazin-1-yl)me...)
Affinity DataIC50: 152nMAssay Description:Inhibition of GST-tagged JAK3 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed