BDBM50311022 CHEMBL1078005::N-(cyanomethyl)-4-(5-methyl-2-(4-morpholinophenylamino)pyrimidin-4-yl)benzamide

SMILES Cc1cnc(Nc2ccc(cc2)N2CCOCC2)nc1-c1ccc(cc1)C(=O)NCC#N

InChI Key InChIKey=PKEOFNLYKBPOQT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311022   

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311022(N-(cyanomethyl)-4-(5-methyl-2-(4-morpholinophenyla...)
Affinity DataIC50: 8nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311022(N-(cyanomethyl)-4-(5-methyl-2-(4-morpholinophenyla...)
Affinity DataIC50: 85nMAssay Description:Inhibition of GST-tagged JAK3 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed