BDBM50311012 CHEMBL1079078::N-(4-(2-(4-(4-hydroxypiperidin-1-yl)phenylamino)pyrimidin-4-yl)phenyl)methanesulfonamide

SMILES CS(=O)(=O)Nc1ccc(cc1)-c1ccnc(Nc2ccc(cc2)N2CCC(O)CC2)n1

InChI Key InChIKey=SNCROWOTWGUING-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311012   

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311012(N-(4-(2-(4-(4-hydroxypiperidin-1-yl)phenylamino)py...)
Affinity DataIC50: 6nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311012(N-(4-(2-(4-(4-hydroxypiperidin-1-yl)phenylamino)py...)
Affinity DataIC50: 149nMAssay Description:Inhibition of GST-tagged JAK3 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed