BDBM50311008 CHEMBL1078866::N-(4-(2-(3-((4-methylpiperazin-1-yl)methyl)phenylamino)pyrimidin-4-yl)phenyl)methanesulfonamide

SMILES CN1CCN(Cc2cccc(Nc3nccc(n3)-c3ccc(NS(C)(=O)=O)cc3)c2)CC1

InChI Key InChIKey=FACHOPIRQYUOES-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311008   

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311008(N-(4-(2-(3-((4-methylpiperazin-1-yl)methyl)phenyla...)
Affinity DataIC50: 14nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311008(N-(4-(2-(3-((4-methylpiperazin-1-yl)methyl)phenyla...)
Affinity DataIC50: 960nMAssay Description:Inhibition of GST-tagged JAK3 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed