BDBM50310988 4-{[2-(methoxycarbonyl)-5-(2-thienyl)-3-thienyl]amino}-4-oxo-2-butenoic acid::4-{[2-methoxycarbonyl)-5-(2-thienyl)-3-thienyl]amino}-4-oxo-2-butenoic acid::CHEMBL1077990

SMILES COC(=O)c1sc(cc1NC(=O)\C=C\C(O)=O)-c1cccs1

InChI Key InChIKey=GJODSFZNKNHKML-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50310988   

TargetFatty acid-binding protein, adipocyte(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50310988(4-{[2-methoxycarbonyl)-5-(2-thienyl)-3-thienyl]ami...)
Affinity DataKi:  670nMAssay Description:Displacement of radiolabeled 1-anilinonaphthalene 8-sulfonic acid from AFABP expressed in Escherichia coli BL21 (DE3) by fluorescence spectrophotomet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetFatty acid-binding protein 5(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50310988(4-{[2-methoxycarbonyl)-5-(2-thienyl)-3-thienyl]ami...)
Affinity DataKi:  3.40E+3nMAssay Description:Displacement of radiolabeled 1-anilinonaphthalene 8-sulfonic acid from EFABP expressed in Escherichia coli BL21 (DE3) by fluorescence spectrophotomet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetFatty acid-binding protein, intestinal(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50310988(4-{[2-methoxycarbonyl)-5-(2-thienyl)-3-thienyl]ami...)
Affinity DataKi:  6.57E+3nMAssay Description:Displacement of radiolabeled 1-anilinonaphthalene 8-sulfonic acid from IFABP expressed in Escherichia coli BL21 (DE3) by fluorescence spectrophotomet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetFatty acid-binding protein, liver(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50310988(4-{[2-methoxycarbonyl)-5-(2-thienyl)-3-thienyl]ami...)
Affinity DataKi:  8.17E+3nMAssay Description:Displacement of radiolabeled 1-anilinonaphthalene 8-sulfonic acid from LFABP expressed in Escherichia coli BL21 (DE3) by fluorescence spectrophotomet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetFatty acid-binding protein, heart(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50310988(4-{[2-methoxycarbonyl)-5-(2-thienyl)-3-thienyl]ami...)
Affinity DataKi:  9.07E+3nMAssay Description:Displacement of radiolabeled 1-anilinonaphthalene 8-sulfonic acid from HFABP expressed in Escherichia coli BL21 (DE3) by fluorescence spectrophotomet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed