BDBM50310798 CHEMBL1078264::N-(4-(1H-indol-5-yl)benzyl)-3-methyl-3-phenylpiperidine-1-carboxamide

SMILES CC1(CCCN(C1)C(=O)NCc1ccc(cc1)-c1ccc2[nH]ccc2c1)c1ccccc1

InChI Key InChIKey=HIQKQNMARNQIET-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50310798   

TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50310798(N-(4-(1H-indol-5-yl)benzyl)-3-methyl-3-phenylpiper...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50310798(N-(4-(1H-indol-5-yl)benzyl)-3-methyl-3-phenylpiper...)
Affinity DataIC50: 6nMAssay Description:Inhibition of rat soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50310798(N-(4-(1H-indol-5-yl)benzyl)-3-methyl-3-phenylpiper...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human soluble epoxide hydrolase in HEK293 cells assessed as DHET productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEpoxide hydrolase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50310798(N-(4-(1H-indol-5-yl)benzyl)-3-methyl-3-phenylpiper...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human microsomal epoxide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50310798(N-(4-(1H-indol-5-yl)benzyl)-3-methyl-3-phenylpiper...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50310798(N-(4-(1H-indol-5-yl)benzyl)-3-methyl-3-phenylpiper...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50310798(N-(4-(1H-indol-5-yl)benzyl)-3-methyl-3-phenylpiper...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Nav1.5 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed