BDBM50310746 (5S)-5-butyl-3-((4,4-difluorocyclohexyl)methyl)-9-(1-(4,6-dimethylpyrimidine-5-carbonyl)-4-methylpiperidin-4-yl)-1-oxa-3,9-diazaspiro[5.5]undecan-2-one::CHEMBL1078714

SMILES CCCC[C@H]1CN(CC2CCC(F)(F)CC2)C(=O)OC11CCN(CC1)C1(C)CCN(CC1)C(=O)c1c(C)ncnc1C

InChI Key InChIKey=ZOUBVRYFOBAGOI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50310746   

TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50310746((5S)-5-butyl-3-((4,4-difluorocyclohexyl)methyl)-9-...)
Affinity DataIC50: 27nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor co-transfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed