BDBM50310690 CHEMBL1078411::Cis-(S)-2-amino-N-((1R,2R)-1-cyano-2-phenylcyclopropyl)-3-(thiophen-2-yl)propanamide

SMILES N[C@@H](Cc1cccs1)C(=O)N[C@@]1(C[C@@H]1c1ccccc1)C#N

InChI Key InChIKey=FUYOZZGSCQXNCB-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50310690   

TargetDipeptidyl peptidase 1(Human)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310690(Cis-(S)-2-amino-N-((1R,2R)-1-cyano-2-phenylcyclopr...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCathepsin B(Human)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310690(Cis-(S)-2-amino-N-((1R,2R)-1-cyano-2-phenylcyclopr...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310690(Cis-(S)-2-amino-N-((1R,2R)-1-cyano-2-phenylcyclopr...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310690(Cis-(S)-2-amino-N-((1R,2R)-1-cyano-2-phenylcyclopr...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetPro-cathepsin H(Human)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310690(Cis-(S)-2-amino-N-((1R,2R)-1-cyano-2-phenylcyclopr...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human cathepsin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCathepsin G(Human)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310690(Cis-(S)-2-amino-N-((1R,2R)-1-cyano-2-phenylcyclopr...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human cathepsin GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310690(Cis-(S)-2-amino-N-((1R,2R)-1-cyano-2-phenylcyclopr...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human Neutrophil elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMyeloblastin(Human)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310690(Cis-(S)-2-amino-N-((1R,2R)-1-cyano-2-phenylcyclopr...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human Proteinase-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed