BDBM50310659 (S)-2,3-dichloro-N-(pyrrolidin-3-yl)-N-(2,2,2-trifluoroethyl)benzamide::CHEMBL1080788

SMILES FC(F)(F)CN([C@H]1CCNC1)C(=O)c1cccc(Cl)c1Cl

InChI Key InChIKey=IUTSKNRONKMGOS-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50310659   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50310659((S)-2,3-dichloro-N-(pyrrolidin-3-yl)-N-(2,2,2-trif...)
Affinity DataKi:  39nMAssay Description:Displacement of [3H]5HT from human 5HT transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandPNGBDBM50310659((S)-2,3-dichloro-N-(pyrrolidin-3-yl)-N-(2,2,2-trif...)
Affinity DataKi:  95nMAssay Description:Displacement of [3H]noradrenaline from human NET receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50310659((S)-2,3-dichloro-N-(pyrrolidin-3-yl)-N-(2,2,2-trif...)
Affinity DataKi:  3.73E+3nMAssay Description:Displacement of [3H]dopamine from human DAT receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandPNGBDBM50310659((S)-2,3-dichloro-N-(pyrrolidin-3-yl)-N-(2,2,2-trif...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed