BDBM50310355 6-(3-amino-1-(3'-hydroxybiphenyl-3-yl)-1H-pyrazol-4-yl)-3,4-dihydroisoquinolin-1(2H)-one::CHEMBL603694

SMILES Nc1nn(cc1-c1ccc2C(=O)NCCc2c1)-c1cccc(c1)-c1cccc(O)c1

InChI Key InChIKey=FRKWUYUWMYUILV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50310355   

TargetMAP kinase-activated protein kinase 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310355(6-(3-amino-1-(3'-hydroxybiphenyl-3-yl)-1H-pyrazol-...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed