BDBM50310278 9-O-[4-(Phenylol-1-yloxy)butyl]berberine bromide::CHEMBL602861

SMILES COc1ccc2cc3-c4cc5OCOc5cc4CC[n+]3cc2c1OCCCCOc1ccccc1

InChI Key InChIKey=BKMOSBYJXKOCTP-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50310278   

TargetCholinesterase(Horse)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50310278(9-O-[4-(Phenylol-1-yloxy)butyl]berberine bromide |...)
Affinity DataIC50: 4.89E+3nMAssay Description:Inhibition of horse serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50310278(9-O-[4-(Phenylol-1-yloxy)butyl]berberine bromide |...)
Affinity DataIC50: 97nMAssay Description:Inhibition of electric eel AChE by modified Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Guangzhou Institute of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50310278(9-O-[4-(Phenylol-1-yloxy)butyl]berberine bromide |...)
Affinity DataIC50: 4.89E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine chloride as substrate preincubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50310278(9-O-[4-(Phenylol-1-yloxy)butyl]berberine bromide |...)
Affinity DataIC50: 97nMAssay Description:Inhibition of electric eel AChE using acetylcholine chloride as substrate preincubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50310278(9-O-[4-(Phenylol-1-yloxy)butyl]berberine bromide |...)
Affinity DataKi:  45nMAssay Description:Inhibition of electric eel AChE by enzyme kinetics assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50310278(9-O-[4-(Phenylol-1-yloxy)butyl]berberine bromide |...)
Affinity DataKi:  1.02E+3nMAssay Description:Inhibition of horse serum BChE by enzyme kinetics assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed