BDBM50310159 CHEMBL590492::rac-2-amino-4-(2-isopropylpyridin-4-yl)-1-methyl-4-(3-(pyrimidin-5-yl)phenyl)-1H-imidazol-5(4H)-one

SMILES CC(C)c1cc(ccn1)C1(N=C(N)N(C)C1=O)c1cccc(c1)-c1cncnc1

InChI Key InChIKey=WEPVSZQVQNITEF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50310159   

TargetBeta-secretase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50310159(rac-2-amino-4-(2-isopropylpyridin-4-yl)-1-methyl-4...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50310159(rac-2-amino-4-(2-isopropylpyridin-4-yl)-1-methyl-4...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50310159(rac-2-amino-4-(2-isopropylpyridin-4-yl)-1-methyl-4...)
Affinity DataIC50: 6.13E+3nMAssay Description:Inhibition of human BACE2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed