BDBM50310155 2-amino-1-methyl-4-(3-(pyridin-3-yl)phenyl)-4-(pyridin-4-yl)-1H-imidazol-5(4H)-one::CHEMBL604590::rac-2-amino-1-methyl-4-(3-(pyridin-3-yl)phenyl)-4-(pyridin-4-yl)-1H-imidazol-5(4H)-one

SMILES CN1C(=O)[C@@](N=C1N)(c2ccncc2)c3cccc(c3)c4cccnc4

InChI Key InChIKey=AIKOTXHNUIYVMD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50310155   

TargetBeta-secretase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50310155(rac-2-amino-1-methyl-4-(3-(pyridin-3-yl)phenyl)-4-...)
Affinity DataIC50: 60nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50310155(rac-2-amino-1-methyl-4-(3-(pyridin-3-yl)phenyl)-4-...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50310155(rac-2-amino-1-methyl-4-(3-(pyridin-3-yl)phenyl)-4-...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50310155(rac-2-amino-1-methyl-4-(3-(pyridin-3-yl)phenyl)-4-...)
Affinity DataIC50: 480nMAssay Description:Inhibition of BACE2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50310155(rac-2-amino-1-methyl-4-(3-(pyridin-3-yl)phenyl)-4-...)
Affinity DataIC50: 480nMAssay Description:Inhibition of human BACE2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed