BDBM50309956 (exo)-N-(3-(cyclopentyloxy)benzyl)-1-methyl-N-(octahydrocyclopenta[c]pyrrol-5-yl)-1H-imidazole-4-carboxamide::CHEMBL603691

SMILES Cn1cnc(c1)C(=O)N(Cc1cccc(OC2CCCC2)c1)[C@@H]1C[C@@H]2CNC[C@@H]2C1

InChI Key InChIKey=PAJUEHORDWKTSQ-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50309956   

LigandPNGBDBM50309956((exo)-N-(3-(cyclopentyloxy)benzyl)-1-methyl-N-(oct...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human glycine transporter 2-mediated glycine uptake expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50309956((exo)-N-(3-(cyclopentyloxy)benzyl)-1-methyl-N-(oct...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50309956((exo)-N-(3-(cyclopentyloxy)benzyl)-1-methyl-N-(oct...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
LigandPNGBDBM50309956((exo)-N-(3-(cyclopentyloxy)benzyl)-1-methyl-N-(oct...)
Affinity DataKi:  5.30nMAssay Description:Displacement of tritiated NPTS from human glycine transporter 1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed