BDBM50309398 2-(4-(4-chlorophenyl)-2-(naphthalen-2-ylmethyl)thiazol-5-yl)acetic acid::CHEMBL589502

SMILES OC(=O)Cc1sc(Cc2ccc3ccccc3c2)nc1-c1ccc(Cl)cc1

InChI Key InChIKey=AOTUDKKSXQEOBL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50309398   

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50309398(2-(4-(4-chlorophenyl)-2-(naphthalen-2-ylmethyl)thi...)
Affinity DataIC50: 41nMAssay Description:Displacement of[3H]PGD2 from human CRTH2 receptor expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50309398(2-(4-(4-chlorophenyl)-2-(naphthalen-2-ylmethyl)thi...)
Affinity DataIC50: 570nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in HEK285-7 cells assessed as inhibition of beta arrestin translocation by bioluminescence reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed