BDBM50309098 3-(4-methyl-1,4-diazepan-1-yl)-5-(pyridin-4-yl)pyrazin-2-amine::CHEMBL602706

SMILES CN1CCCN(CC1)c1nc(cnc1N)-c1ccncc1

InChI Key InChIKey=PIMQFHNTBSHECK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50309098   

TargetRho-associated protein kinase 2(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50309098(3-(4-methyl-1,4-diazepan-1-yl)-5-(pyridin-4-yl)pyr...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human recombinant ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50309098(3-(4-methyl-1,4-diazepan-1-yl)-5-(pyridin-4-yl)pyr...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human recombinant ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed