BDBM50309000 CHEMBL589819::N-((5'-chloro-3,3'-difluoro-2'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl)methyl)-1-ethyl-2-(3-methoxyisoxazole-5-carbonyl)hydrazinecarboxamide

SMILES CCN(NC(=O)c1cc(OC)no1)C(=O)NCc1ccc(cc1F)-c1cc(Cl)cc(F)c1-c1noc(C)n1

InChI Key InChIKey=AGCQXBIRJFMROF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50309000   

TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309000(N-((5'-chloro-3,3'-difluoro-2'-(5-methyl-1,2,4-oxa...)
Affinity DataIC50: 0.430nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells assessed as inhibition of des-Arg-bradykinin-mediated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed