BDBM50308907 3-[2-({[(1S)-1-(1-Naphthyl)ethyl]amino}carbonyl)-4-(phenoxymethyl)phenyl]propanoic acid::CHEMBL599355

SMILES C[C@H](NC(=O)c1cc(COc2ccccc2)ccc1CCC(O)=O)c1cccc2ccccc12

InChI Key InChIKey=VPXMPIBOESHHAF-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50308907   

TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50308907(3-[2-({[(1S)-1-(1-Naphthyl)ethyl]amino}carbonyl)-4...)
Affinity DataIC50: 9.50E+3nMAssay Description:Antagonist activity at mouse EP3alpha receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50308907(3-[2-({[(1S)-1-(1-Naphthyl)ethyl]amino}carbonyl)-4...)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]PGE3alpha from mouse EP3alpha receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50308907(3-[2-({[(1S)-1-(1-Naphthyl)ethyl]amino}carbonyl)-4...)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [3H]PGE3 from mouse EP4 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50308907(3-[2-({[(1S)-1-(1-Naphthyl)ethyl]amino}carbonyl)-4...)
Affinity DataKi:  9.20E+3nMAssay Description:Displacement of [3H]PGE2 from mouse EP2 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50308907(3-[2-({[(1S)-1-(1-Naphthyl)ethyl]amino}carbonyl)-4...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGE2 from mouse EP1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed