BDBM50308902 3-[2-{[(1-Naphthylmethyl)amino]carbonyl}-4-(phenoxymethyl)phenyl]propanoic acid::CHEMBL589411

SMILES OC(=O)CCc1ccc(COc2ccccc2)cc1C(=O)NCc1cccc2ccccc12

InChI Key InChIKey=SUQUIWQFSXZDOM-UHFFFAOYSA-N

Data  4 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50308902   

TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50308902(3-[2-{[(1-Naphthylmethyl)amino]carbonyl}-4-(phenox...)
Affinity DataIC50: 770nMAssay Description:Antagonist activity at mouse EP3alpha receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50308902(3-[2-{[(1-Naphthylmethyl)amino]carbonyl}-4-(phenox...)
Affinity DataIC50: 68nMAssay Description:Antagonist activity at mouse EP3alpha receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50308902(3-[2-{[(1-Naphthylmethyl)amino]carbonyl}-4-(phenox...)
Affinity DataIC50: 3.20E+3nMAssay Description:Antagonist activity at mouse EP3alpha receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50308902(3-[2-{[(1-Naphthylmethyl)amino]carbonyl}-4-(phenox...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]PGE3alpha from mouse EP3alpha receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50308902(3-[2-{[(1-Naphthylmethyl)amino]carbonyl}-4-(phenox...)
Affinity DataKi:  340nMAssay Description:Displacement of [3H]PGE3 from mouse EP4 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50308902(3-[2-{[(1-Naphthylmethyl)amino]carbonyl}-4-(phenox...)
Affinity DataKi:  1.50E+3nMAssay Description:Displacement of [3H]PGE2 from mouse EP2 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50308902(3-[2-{[(1-Naphthylmethyl)amino]carbonyl}-4-(phenox...)
Affinity DataKi:  5.00E+3nMAssay Description:Displacement of [3H]PGE2 from mouse EP1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed