BDBM50308646 1-(5-Bromo-2-hydroxybenzyl)-1-(4-fluorobenzyl)-3-phenylurea::CHEMBL592427

SMILES Oc1c(Br)cccc1CN(Cc1ccc(F)cc1)C(=O)Nc1ccccc1

InChI Key InChIKey=DOFNHGGYAVHZBW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50308646   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50308646(1-(5-Bromo-2-hydroxybenzyl)-1-(4-fluorobenzyl)-3-p...)
Affinity DataIC50: 5.17E+3nMAssay Description:Inhibition of human cloned HER2 autophosphorylation expressed in baculovirus-infected Sf9 cells by solid-phase ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50308646(1-(5-Bromo-2-hydroxybenzyl)-1-(4-fluorobenzyl)-3-p...)
Affinity DataIC50: 2.24E+3nMAssay Description:Inhibition of cloned EGFR autophosphorylation expressed in baculovirus-infected Sf9 cells by solid-phase ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed