BDBM50308643 1-(3,5-Dibromo-2-hydroxybenzyl)-1-(4-fluorobenzyl)-3-phenylurea::CHEMBL603186

SMILES Oc1c(Br)cc(Br)cc1CN(Cc1ccc(F)cc1)C(=O)Nc1ccccc1

InChI Key InChIKey=XCGWRJUUHHWCDA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50308643   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50308643(1-(3,5-Dibromo-2-hydroxybenzyl)-1-(4-fluorobenzyl)...)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of human cloned HER2 autophosphorylation expressed in baculovirus-infected Sf9 cells by solid-phase ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50308643(1-(3,5-Dibromo-2-hydroxybenzyl)-1-(4-fluorobenzyl)...)
Affinity DataIC50: 4.68E+3nMAssay Description:Inhibition of cloned EGFR autophosphorylation expressed in baculovirus-infected Sf9 cells by solid-phase ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed