BDBM50308533 CHEMBL589254::Methyl (14E)-14-ethylidene-6-methoxy-2-methyl-19-({[(2E)-3-phenylprop-2-enoyl]oxy}methyl)-18-oxa-2,12-diazahexacyclo[9.6.1.1^{9,15}.0^{1,9}.0^{3,8}.0^{12,17}]nonadeca-3(8),4,6-triene-19-carboxylate

SMILES COC(=O)[C@]1(COC(=O)\C=C\c2ccccc2)[C@H]2C[C@@H]3N(C\C2=C\C)[C@@H]2C[C@]11c4cc(OC)ccc4N(C)[C@]31O2

InChI Key InChIKey=AGIAKZIUEDYVAM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50308533   

TargetSodium/glucose cotransporter 1(Human)
Hoshi University

Curated by ChEMBL
LigandPNGBDBM50308533(Methyl (14E)-14-ethylidene-6-methoxy-2-methyl-19-(...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of alpha-D-[U-14C]glucopyranoside uptake at human SGLT1 expressed in african green monkey COS1 cells after 30 mins by liquid scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Hoshi University

Curated by ChEMBL
LigandPNGBDBM50308533(Methyl (14E)-14-ethylidene-6-methoxy-2-methyl-19-(...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of alpha-D-[U-14C]glucopyranoside uptake at human SGLT2 expressed in african green monkey COS1 cells after 30 mins by liquid scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed