BDBM50308515 2-Methoxy-7-methyl-2-oxo-2,3,4,5-tetrahydro-2lambda*5*-[1,2]oxaphosphepine-6-carboxylic acid methyl ester::CHEMBL592624

SMILES COC(=O)C1=C(C)OP(=O)(CCC1)OC

InChI Key InChIKey=GYEHUGPUFOMJON-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50308515   

TargetAcetylcholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50308515(2-Methoxy-7-methyl-2-oxo-2,3,4,5-tetrahydro-2lambd...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human AChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50308515(2-Methoxy-7-methyl-2-oxo-2,3,4,5-tetrahydro-2lambd...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human AChE at pH 8More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50308515(2-Methoxy-7-methyl-2-oxo-2,3,4,5-tetrahydro-2lambd...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of human AChE at pH 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50308515(2-Methoxy-7-methyl-2-oxo-2,3,4,5-tetrahydro-2lambd...)
Affinity DataKi:  7.60E+4nMAssay Description:Inhibition of human AChE assessed as equilibrium binding by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed