BDBM50308487 CHEMBL591710::N-(5-Benzoyl-4-phenylthiazol-2-yl)furan-2-carboxamide

SMILES O=C(Nc1nc(c(s1)C(=O)c1ccccc1)-c1ccccc1)c1ccco1

InChI Key InChIKey=IKMNLKQUUGRBCM-UHFFFAOYSA-N

Data  6 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50308487   

TargetAdenosine receptor A1(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50308487(N-(5-Benzoyl-4-phenylthiazol-2-yl)furan-2-carboxam...)
Affinity DataIC50: 29nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor in rat brain cortical membrane in presence of 100 uM GTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50308487(N-(5-Benzoyl-4-phenylthiazol-2-yl)furan-2-carboxam...)
Affinity DataIC50: 25nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor in rat brain cortical membrane in absence of 100 uM GTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50308487(N-(5-Benzoyl-4-phenylthiazol-2-yl)furan-2-carboxam...)
Affinity DataKi:  5.80nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in rat brain cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50308487(N-(5-Benzoyl-4-phenylthiazol-2-yl)furan-2-carboxam...)
Affinity DataKi:  54nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50308487(N-(5-Benzoyl-4-phenylthiazol-2-yl)furan-2-carboxam...)
Affinity DataKi:  208nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50308487(N-(5-Benzoyl-4-phenylthiazol-2-yl)furan-2-carboxam...)
Affinity DataKi:  348nMAssay Description:Displacement of [3H]MSX2 from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50308487(N-(5-Benzoyl-4-phenylthiazol-2-yl)furan-2-carboxam...)
Affinity DataKi:  662nMAssay Description:Displacement of [3H]MSX2 from adenosine A2A receptor in rat brain striatum membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50308487(N-(5-Benzoyl-4-phenylthiazol-2-yl)furan-2-carboxam...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]PSB-603 from human adenosine A2B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed