BDBM50308445 (2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-(2-methylpyridin-4-yl)-1,3,4-thiadiazol-2-yl)methyl)phenyl)-6-(hydroxymethyl)-tetrahydro-2H-pyran-3,4,5-triol::CHEMBL600982::US8541380, 45

SMILES Cc1cc(ccn1)-c1nnc(Cc2cc(ccc2Cl)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)s1

InChI Key InChIKey=XLYBELAZFYADEG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50308445   

TargetSodium/glucose cotransporter 2(Human)
Green Cross

US Patent
LigandPNGBDBM50308445(US8541380, 45 | CHEMBL600982 | (2S,3R,4R,5S,6R)-2-...)
Affinity DataIC50: 36.4nMAssay Description:Inhibition assay using hSGLT2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2013
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 2(Human)
Green Cross

US Patent
LigandPNGBDBM50308445(US8541380, 45 | CHEMBL600982 | (2S,3R,4R,5S,6R)-2-...)
Affinity DataIC50: 36.4nMAssay Description:Inhibition of human recombinant SGLT2 expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed