BDBM50308192 2-(4-Methoxyanilino)-9-methoxy-5,7-dihydro-6H-pyrimido[5,4-d][1]benzazepin-6-one::CHEMBL606395

SMILES COc1ccc(Nc2ncc3CC(=O)Nc4cc(OC)ccc4-c3n2)cc1

InChI Key InChIKey=SKCATAJFICHYLV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50308192   

TargetSerine/threonine-protein kinase PLK1(Human)
Technische Universitat Braunschweig

Curated by ChEMBL
LigandPNGBDBM50308192(2-(4-Methoxyanilino)-9-methoxy-5,7-dihydro-6H-pyri...)
Affinity DataIC50: 350nMAssay Description:Inhibition of PLK1 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Technische Universitat Braunschweig

Curated by ChEMBL
LigandPNGBDBM50308192(2-(4-Methoxyanilino)-9-methoxy-5,7-dihydro-6H-pyri...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of INSR assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Technische Universitat Braunschweig

Curated by ChEMBL
LigandPNGBDBM50308192(2-(4-Methoxyanilino)-9-methoxy-5,7-dihydro-6H-pyri...)
Affinity DataIC50: 50nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed