BDBM50308182 (3R)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyrrolidin-3-amine::CHEMBL604102

SMILES N[C@@H]1CCN(C1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12

InChI Key InChIKey=OPTAOWZLDMSBKX-UHFFFAOYSA-N

Data  7 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50308182   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308182((3R)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...)
Affinity DataIC50: 15.7nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells assessed as intracellular cAMP formation by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308182((3R)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...)
Affinity DataKi:  4.46nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308182((3R)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...)
Affinity DataKi:  274nMAssay Description:Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308182((3R)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...)
Affinity DataKi:  2.27E+3nMAssay Description:Binding affinity to 5HT1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308182((3R)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...)
Affinity DataKi:  2.91E+3nMAssay Description:Binding affinity to dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308182((3R)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...)
Affinity DataKi:  4.73E+3nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308182((3R)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...)
Affinity DataKi:  6.04E+3nMAssay Description:Binding affinity to 5HT1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308182((3R)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to alpha2A adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed