BDBM50308163 3-Ethynyl-6-hydroxy-1-methyl-2-phenyl-1H-indole-5-carboxylic Acid::CHEMBL603136

SMILES Cn1c(c(C#C)c2cc(C(O)=O)c(O)cc12)-c1ccccc1

InChI Key InChIKey=KITBACSQDSZRCY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50308163   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50308163(3-Ethynyl-6-hydroxy-1-methyl-2-phenyl-1H-indole-5-...)
Affinity DataIC50: 2.12E+5nMpH: 7.0Assay Description:Inhibition of SHP2 Src homology-2 domain expressed in Escherichia coli BL21 (DE3) assessed as inhibition of p-nitrophenyl phosphate hydrolysis at pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed