BDBM50308147 1-[4-(4,6-Dimorpholin-4-yl-1,3,5-triazin-2-yl)-phenyl]-3-[4-(hydroxymethyl)phenyl]urea::CHEMBL597004

SMILES OCc1ccc(NC(=O)Nc2ccc(cc2)-c2nc(nc(n2)N2CCOCC2)N2CCOCC2)cc1

InChI Key InChIKey=MIPSHXJPVYIDDC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50308147   

LigandPNGBDBM50308147(1-[4-(4,6-Dimorpholin-4-yl-1,3,5-triazin-2-yl)-phe...)
Affinity DataIC50: 1nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
LigandPNGBDBM50308147(1-[4-(4,6-Dimorpholin-4-yl-1,3,5-triazin-2-yl)-phe...)
Affinity DataIC50: 14.5nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308147(1-[4-(4,6-Dimorpholin-4-yl-1,3,5-triazin-2-yl)-phe...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed