BDBM50307981 4-(2-Chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-amine::CHEMBL598439::US8796293, 55

SMILES NC1(Cc2ccccc2Cl)CCN(CC1)c1ncnc2[nH]ccc12

InChI Key InChIKey=ZIJXGYJGMQFIDA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50307981   

TargetRho-associated protein kinase 2(Human)
The Institute of Cancer Research

US Patent
LigandPNGBDBM50307981(US8796293, 55 | CHEMBL598439 | 4-(2-Chlorobenzyl)-...)
Affinity DataIC50: 1.00E+3nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 ul, ROCK-II (h) (5-10 mU) is incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 uM KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
Go to US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50307981(US8796293, 55 | CHEMBL598439 | 4-(2-Chlorobenzyl)-...)
Affinity DataIC50: 44nMAssay Description:Inhibition of PKBbeta by radiometric filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed