BDBM50307940 CHEMBL603266::N-(4-(3-Bromoanilino)quinazolin-6-yl)-2-(3-oxoisothiazolin-2-yl)acetamide

SMILES Brc1cccc(Nc2ncnc3ccc(NC(=O)Cn4sccc4=O)cc23)c1

InChI Key InChIKey=XEJKUBDGAQQSNP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50307940   

TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50307940(N-(4-(3-Bromoanilino)quinazolin-6-yl)-2-(3-oxoisot...)
Affinity DataIC50: 0.360nMAssay Description:Inhibition of human recombinant EGFR expressed in insect cells by time-resolved fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50307940(N-(4-(3-Bromoanilino)quinazolin-6-yl)-2-(3-oxoisot...)
Affinity DataIC50: 0.360nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed