BDBM50307860 (S)-N-(4-carbamimidoylbenzyl)-1-propionylpyrrolidine-2-carboxamide hydrochloride::CHEMBL599036

SMILES CCC(=O)N1CCC[C@H]1C(=O)NCc1ccc(cc1)C(N)=N

InChI Key InChIKey=PJYGFNKKYSSLPL-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50307860   

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307860((S)-N-(4-carbamimidoylbenzyl)-1-propionylpyrrolidi...)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2016
Entry Details Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307860((S)-N-(4-carbamimidoylbenzyl)-1-propionylpyrrolidi...)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibition of human alpha-thrombin using chromogenic substrate Pefachrome tPa measured every second for 20 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307860((S)-N-(4-carbamimidoylbenzyl)-1-propionylpyrrolidi...)
Affinity DataKi:  3.90E+4nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed