BDBM50307832 (+)-4-(4-(2-((5-Hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)(propyl)amino)ethyl)piperazin-1-yl)quinolin-8-ol::(-)-4-(4-(2-((5-Hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)(propyl)amino)ethyl)piperazin-1-yl)quinolin-8-ol::4-(4-(2-((5-Hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)(propyl)amino)ethyl)piperazin-1-yl)quinolin-8-ol::CHEMBL599636

SMILES CCCN(CCN1CCN(CC1)c1ccnc2c(O)cccc12)C1CCc2c(O)cccc2C1

InChI Key InChIKey=SWEZRIWMOXWKPT-UHFFFAOYSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50307832   

TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50307832(4-(4-(2-((5-Hydroxy-1,2,3,4-tetrahydronaphthalen-2...)
Affinity DataEC50:  4.51nMAssay Description:Agonist activity at human dopamine D2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50307832(4-(4-(2-((5-Hydroxy-1,2,3,4-tetrahydronaphthalen-2...)
Affinity DataEC50:  1.58nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50307832(4-(4-(2-((5-Hydroxy-1,2,3,4-tetrahydronaphthalen-2...)
Affinity DataKi:  7.73nMAssay Description:Displacement of [3H]spiperone from cloned dopamine D3 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50307832(4-(4-(2-((5-Hydroxy-1,2,3,4-tetrahydronaphthalen-2...)
Affinity DataKi:  7.73nMAssay Description:Displacement of [3H]spiperone from cloned dopamine D3 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50307832(4-(4-(2-((5-Hydroxy-1,2,3,4-tetrahydronaphthalen-2...)
Affinity DataKi:  7.73nMAssay Description:Displacement of [3H]spiperone from cloned dopamine D3 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed