BDBM50307783 CHEMBL597773::N1-(4-(3-chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl)-N8-hydroxyoctanediamide

SMILES COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)CCCCCCC(=O)NO

InChI Key InChIKey=SNGQUXXOIHSAPK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50307783   

TargetEpidermal growth factor receptor(Human)
Curis

Curated by ChEMBL
LigandPNGBDBM50307783(N1-(4-(3-chloro-4-fluorophenylamino)-7-methoxyquin...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
LigandPNGBDBM50307783(N1-(4-(3-chloro-4-fluorophenylamino)-7-methoxyquin...)
Affinity DataIC50: 20nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed