BDBM50307776 7-(4-(3-Ethynyl-4-fluorophenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanamide::CHEMBL598798

SMILES COc1cc2ncnc(Nc3ccc(F)c(c3)C#C)c2cc1OCCCCCCC(=O)NO

InChI Key InChIKey=ISCACOSJZYPVNU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50307776   

TargetEpidermal growth factor receptor(Human)
Curis

Curated by ChEMBL
LigandPNGBDBM50307776(7-(4-(3-Ethynyl-4-fluorophenylamino)-7-methoxyquin...)
Affinity DataIC50: 29nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
LigandPNGBDBM50307776(7-(4-(3-Ethynyl-4-fluorophenylamino)-7-methoxyquin...)
Affinity DataIC50: 77nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Menoufia University

Curated by ChEMBL
LigandPNGBDBM50307776(7-(4-(3-Ethynyl-4-fluorophenylamino)-7-methoxyquin...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of HDAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Curis

Curated by ChEMBL
LigandPNGBDBM50307776(7-(4-(3-Ethynyl-4-fluorophenylamino)-7-methoxyquin...)
Affinity DataIC50: 29nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50307776(7-(4-(3-Ethynyl-4-fluorophenylamino)-7-methoxyquin...)
Affinity DataIC50: 77nMAssay Description:Inhibition of HER2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed