BDBM50307480 CHEMBL579296::Pyrazine-2-carboxylic acid(1-[3-methyl-1-(2,9,9-trimethyl-3,5-dioxa-4-boratri-cyclo[6.1.1.02,6]dec-4-yl)-butylcarbamoyl]-2-(3,5-bis(trifluoromethyl)phenyl)ethyl)-amide

SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)NC(=O)c1cnccn1)B1OC2C[C@@H]3C[C@@H](C3(C)C)[C@]2(C)O1

InChI Key InChIKey=MVMFLLQZEBCPKK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50307480   

TargetProteasome subunit beta type-1(Human)
Gorlaeus Laboratories

Curated by ChEMBL
LigandPNGBDBM50307480(Pyrazine-2-carboxylic acid(1-[3-methyl-1-(2,9,9-tr...)
Affinity DataIC50: 160nMAssay Description:Inhibition of 26S proteasome beta 1 using nLPnLD as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Gorlaeus Laboratories

Curated by ChEMBL
LigandPNGBDBM50307480(Pyrazine-2-carboxylic acid(1-[3-methyl-1-(2,9,9-tr...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of 26S proteasome beta 2 using RLR as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Gorlaeus Laboratories

Curated by ChEMBL
LigandPNGBDBM50307480(Pyrazine-2-carboxylic acid(1-[3-methyl-1-(2,9,9-tr...)
Affinity DataIC50: 3nMAssay Description:Inhibition of 26S proteasome beta 5 using LLVY as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed