BDBM50307463 (1S,2R)-1-(3-Fluorophenyl)-3-(methylamino)-1-(2-methyl-2,3-dihydro-1H-indol-1-yl)propan-2-ol Hydrochloride::CHEMBL605213

SMILES CNC[C@@H](O)[C@@H](N1C(C)Cc2ccccc12)c1cccc(F)c1

InChI Key InChIKey=LXDDMNMCPHMWJN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50307463   

TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50307463((1S,2R)-1-(3-Fluorophenyl)-3-(methylamino)-1-(2-me...)
Affinity DataIC50: 72nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50307463((1S,2R)-1-(3-Fluorophenyl)-3-(methylamino)-1-(2-me...)
Affinity DataIC50: 84nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed