BDBM50307425 3-[2-({[1-(3,4-Dimethoxyphenyl)-3-methylbutyl]amino}-carbonyl)-4-(phenoxymethyl)phenyl]propanoic acid::CHEMBL597160

SMILES COc1ccc(cc1OC)C(CC(C)C)NC(=O)c1cc(COc2ccccc2)ccc1CCC(O)=O

InChI Key InChIKey=MOTOKILOGAVSPV-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50307425   

TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50307425(3-[2-({[1-(3,4-Dimethoxyphenyl)-3-methylbutyl]amin...)
Affinity DataIC50: 24nMAssay Description:Antagonist activity at mouse EP3 receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase intracellular calcium level in prese...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50307425(3-[2-({[1-(3,4-Dimethoxyphenyl)-3-methylbutyl]amin...)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed