BDBM50307109 3-acetyl-11-keto-ursolic acid::CHEMBL601891

SMILES C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC(=O)[C@@H]4[C@@]5(C)CC[C@H](OC(C)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2[C@H]1C)C(O)=O

InChI Key InChIKey=XDHCWTUZCOFKRH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50307109   

LigandPNGBDBM50307109(3-acetyl-11-keto-ursolic acid | CHEMBL601891)
Affinity DataIC50: 1.12E+4nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50307109(3-acetyl-11-keto-ursolic acid | CHEMBL601891)
Affinity DataIC50: 1.15E+4nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B3-transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50307109(3-acetyl-11-keto-ursolic acid | CHEMBL601891)
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as reduction of cortisone to cortisol conversion by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed