BDBM50307064 4-nitrophenyl 4-(bis(4-fluorophenyl)methyl)piperazine-1-carboxylate::CHEMBL602499

SMILES [O-][N+](=O)c1ccc(OC(=O)N2CCN(CC2)C(c2ccc(F)cc2)c2ccc(F)cc2)cc1

InChI Key InChIKey=HGVVCSZODUSUMM-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50307064   

TargetMonoglyceride lipase(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50307064(4-nitrophenyl 4-(bis(4-fluorophenyl)methyl)piperaz...)
Affinity DataIC50: 347nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2016
Entry Details Article
PubMed
TargetMonoacylglycerol lipase ABHD6(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50307064(4-nitrophenyl 4-(bis(4-fluorophenyl)methyl)piperaz...)
Affinity DataIC50: 900nMAssay Description:Inhibition of ABHD6 in mouse brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50307064(4-nitrophenyl 4-(bis(4-fluorophenyl)methyl)piperaz...)
Affinity DataIC50: 5.41E+3nMAssay Description:Inhibition of FAAH in mouse brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50307064(4-nitrophenyl 4-(bis(4-fluorophenyl)methyl)piperaz...)
Affinity DataIC50: 200nMAssay Description:Inhibition of MAGL in mouse brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50307064(4-nitrophenyl 4-(bis(4-fluorophenyl)methyl)piperaz...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of rat MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50307064(4-nitrophenyl 4-(bis(4-fluorophenyl)methyl)piperaz...)
Affinity DataIC50: 282nMAssay Description:Inhibition of mouse MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed