BDBM50306891 (7-(3,4-dichlorophenyl)-5-methyl-4,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl)(2-(4-fluorophenyl)pyrrolidin-1-yl)methanone::CHEMBL605576

SMILES CC1=Nc2ccnn2C(C1C(=O)N1CCCC1c1ccc(F)cc1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=HLUPWWBAEWIMAO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50306891   

TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306891((7-(3,4-dichlorophenyl)-5-methyl-4,7-dihydropyrazo...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306891((7-(3,4-dichlorophenyl)-5-methyl-4,7-dihydropyrazo...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306891((7-(3,4-dichlorophenyl)-5-methyl-4,7-dihydropyrazo...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306891((7-(3,4-dichlorophenyl)-5-methyl-4,7-dihydropyrazo...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed