BDBM50306734 CHEMBL603278::isopropyl 3-(3,4-difluorobenzoyl)-9-fluoro-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate

SMILES CC(C)OC(=O)C1=CN(CC(C)(C)c2c1[nH]c1ccc(F)cc21)C(=O)c1ccc(F)c(F)c1

InChI Key InChIKey=ARRGMAZDPUJWJZ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50306734   

TargetBile acid receptor(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306734(isopropyl 3-(3,4-difluorobenzoyl)-9-fluoro-1,1-dim...)
Affinity DataEC50:  112nMAssay Description:Agonist activity at mouse FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306734(isopropyl 3-(3,4-difluorobenzoyl)-9-fluoro-1,1-dim...)
Affinity DataEC50:  45nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed